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网友点评-Thesize and summarize the very best readily available evidence around the use of-线缆测高仪,超声波测高仪, 手持式测高仪-上海交通大学科技园上海野豹企业发展公司
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Thesize and summarize the very best readily available evidence around the use of
The aim of this comparative effectiveness review would be to evaluate the efficacy and side 1742-4682-8-26 impact profile to aid in decision 1874285801105010000 generating.Study IdentificationPreviously described information 1,2,3,4,6-Penta-O-galloyl-beta-D-glucopyranose custom synthesis Sources had been searched by two independent reviewers (TS BF); they reviewed the abstracts, agreed on a-priori eligibility criteria which includes the inclusion and exclusion criteria of every (��)-Veralipride web single study and decided which in the eligible research to contain. One particular review author extracted the information from integrated studies, as well as a second author verified the extracted data. Disagreements had been resolved by discussion in between the two review authors. The number of events in every single trial was extracted, when accessible, on the basis in the intention-to-treat method. For collected and abstracted data, please see Table 1.METHODSThe study was performed following procedures suggested by the Cochrane collaboration12 and is reported in accordance together with the recommendations set forth by the Preferred Reporting Things for Systematic Evaluations and Meta-Analyses (PRISMA) statement.Eligibility CriteriaWe integrated randomized controlled trials that enrolled wholesome peri-menopausal females in the beginning on the study who received any SSRI drugs (e.g., citalopram, escitalopram, fluoxetine, paroxetine, sertraline, and so on.), compared them against placebo or other SSRIs, and evaluated vasomotor symptoms (everyday hot flash frequency or improvement in vasomotor scores). We specifically excluded research that enrolled cancer individuals and sufferers receiving selective estrogen receptor modulators (SERMs) since hot flashes and night sweats are frequent complaints (up to 80 ) of patients getting tamoxifen for breast cancer,14?six ladies taking hormonal replacement therapy and individuals with diagnoses of depression.Facts Sources and Search MethodsA complete literature search was conducted by an professional reference librarian. We searched the electronic databases (MEDLINETM, EMBASE, the Cochrane Central Register of Controlled Trials CENTRAL, Net of Science and Scopus) using various 16173461103300300 combinations of controlled terms: "menopause," post-menopause," "peri-menopause", "hot flushes," "hot flashes," "SSRIs," "climacteric" and "vasomotor." No limits were applied for publication date or language, and foreign papers were translated. We searched by means of March 2013.Figure 1. Flow chart of your study.Table 1. Characteristics of Included Studies Main outcomes Frequency of hot.Thesize and summarize the most effective offered evidence around the use of SSRIs to treat hot flashes in healthier menopausal females. The aim of this comparative effectiveness review should be to evaluate the efficacy and side 1742-4682-8-26 effect profile to help in decision 1874285801105010000 making.Study IdentificationPreviously described data sources were searched by two independent reviewers (TS BF); they reviewed the abstracts, agreed on a-priori eligibility criteria which includes the inclusion and exclusion criteria of every single study and decided which from the eligible studies to consist of. Disagreements amongst reviewers had been resolved by consensus. The kappa statistic for agreement on study selection was 0.87. If a study was deemed relevant, the manuscript was obtained and reviewed in full text versions for additional assessment. The final search identified 61 RCTs; of these, 11 fulfilled the inclusion criteria (Fig. 1).Data Collection and ExtractionData from integrated studies have been extracted by two independent reviewers (TS and FH) using a standardized, piloted data extraction sheet. We abstracted data on patient demographics and baseline characteristics (which includes age, menopause status, race, smoking status and physique mass index); study design and style; sample size; intervention sort [including variety and dose with the SSRI (selective serotonin reuptake inhibitor) versus placebo or versus the form and dose of another SSRI]; type of outcome measure (like the frequency of hot flashes, improvement within the vasomotor score of a validated scale).
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